학술논문

Atrial function analysis after percutaneous umbrella device and suture-mediated patent fossa ovalis closure.
Document Type
Academic Journal
Author
Tarsia C; Unit of Cardiology, Sant'Eugenio Hospital, Rome, Italy.; Gaspardone C; Vita-Salute San Raffaele University, Milan, Italy.; Sgueglia GA; Unit of Cardiology, Sant'Eugenio Hospital, Rome, Italy.; DE Santis A; Unit of Cardiology, Sant'Eugenio Hospital, Rome, Italy.; D'Ascoli E; Unit of Cardiology, Sant'Eugenio Hospital, Rome, Italy.; Piccioni F; Unit of Cardiology, Sant'Eugenio Hospital, Rome, Italy.; Iamele M; Unit of Cardiology, Sant'Eugenio Hospital, Rome, Italy.; Posteraro GA; Unit of Cardiology, Sant'Eugenio Hospital, Rome, Italy.; Cinque A; Unit of Cardiology, Sant'Eugenio Hospital, Rome, Italy.; Gaspardone A; Unit of Cardiology, Sant'Eugenio Hospital, Rome, Italy - a_gaspardone@yahoo.com.
Source
Publisher: Minerva medica Country of Publication: Italy NLM ID: 101776555 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2724-5772 (Electronic) Linking ISSN: 27245683 NLM ISO Abbreviation: Minerva Cardiol Angiol Subsets: MEDLINE
Subject
Language
English
Abstract
Background: Atrial fibrillation is an undesirable event following percutaneous patent fossa ovalis (PFO) closure with metallic occluders, suggesting that implanting a rigid closure device could alter atrial function. Suture-mediated PFO closure is a new technique, achieving closure of the PFO by means of a simple suture. Aim of this study was to evaluate left atrial function after closure of PFO by direct suture and traditional occluders.
Methods: We studied 40 age and sex homogeneous patients, 20 undergoing PFO closure by device (OCL) and 20 by suturing (NS). Twenty healthy sex-age matched subjects made up the control group (CT). Left atrial function was evaluated by using volumetric and speckle-tracking analysis assessing the following parameters: total emptying fraction (EF), Expansion Index (EI), active emptying fraction (AEF), strain values of the reservoir (r-ED), conduit (cd-ED) and contraction phase (ct-ED).
Results: Compared to CT and NS, OCL patients had significantly worst indices of left atrial reservoir function (EF P=0.001, EI P=0.003, r-ED P<0.001), conduit function (cd-ED P=0.018) and contraction function (AEF P=0.010; ct-ED P<0.001). No significant differences were observed in left atrial function indices between CT and NS patients.
Conclusions: Suture-mediated PFO closure does not alter left atrial function. Conversely, metallic occluder is associated with worse left atrium function. This detrimental effect on atrial function could favor the development of atrial arrhythmias.