학술논문

Sero-antigen prevalence of lymphatic filariasis and risk factors of podoconiosis in Busiriba sub-county, Kamwenge district, Southwestern Uganda, August-September 2018.
Document Type
Academic Journal
Author
Mwesigye V; Department of Medical Laboratory Sciences Faculty of Medicine, Mbarara University of Science and Technology, P.O Box 1410, Mbarara, Uganda. vmwesigye@must.ac.ug.; Musinguzi B; Department of Medical Laboratory Sciences, Faculty of Health Sciences, Muni University, P.O Box 725, Arua, Uganda.; Okongo B; Department of Medical Laboratory Sciences Faculty of Medicine, Mbarara University of Science and Technology, P.O Box 1410, Mbarara, Uganda.; Mucunguzi W; District Health Office Kamwenge District, P.O Box 1408, Kamwenge, Uganda.; Kakaire MN; Department of Medical Laboratory Sciences Faculty of Medicine, Mbarara University of Science and Technology, P.O Box 1410, Mbarara, Uganda.; Migisha R; Department of Physiology, Faculty of Medicine, Mbarara University of Science and Technology, P.O Box 1410, Mbarara, Uganda.
Source
Publisher: Biomed Central Country of Publication: England NLM ID: 101462768 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-0500 (Electronic) Linking ISSN: 17560500 NLM ISO Abbreviation: BMC Res Notes Subsets: MEDLINE
Subject
Language
English
Abstract
Objective: Given the neglected nature of filariasis, especially in Uganda where data are scarce, this cross-sectional study aimed to determine the sero-antigen prevalence of lymphatic filariasis and risk factors associated with non-lymphatic filariasis (podoconiosis) in Busiriba Sub-county, Kamwenge District, Uganda, during August-September 2018, to inform targeted elimination efforts.
Results: We enrolled 101 participants, among whom 35 (34.7%) had podoconiosis. The sero-antigen prevalence of lymphatic filariasis was 1.0%. Older age and walking barefoot were associated with increased podoconiosis risk. Specifically, individuals aged 25-49 years with had 7.38 times higher odds of podoconiosis (adjusted odds ratio [aOR] = 7.38, 95% CI: 1.36-40.13) compared to those under 25 years, while those aged ≥ 50 years had even higher odds (aOR = 8.49, 95%CI: 1.44-50.15). Additionally, individuals who reported walking barefoot had 14 times higher odds of podoconiosis (aOR = 14.08; 95% CI: 2.49-79.50).
(© 2024. The Author(s).)