학술논문
Direct Synthesis of 3-Aryl Substituted Isocoumarins and Phthalides through Palladium Acetate Catalyzed C(sp 2 )-H Activation in Ionic Liquids.
Document Type
Academic Journal
Author
Aloia A; Chemistry Department, Università degli Studi di Bari Aldo Moro, Via Orabona 4, 70126, Bari, Italy.; Casiello M; Chemistry Department, Università degli Studi di Bari Aldo Moro, Via Orabona 4, 70126, Bari, Italy.; D'Accolti L; Chemistry Department, Università degli Studi di Bari Aldo Moro, Via Orabona 4, 70126, Bari, Italy.; CNR - Istituto di Chimica dei Composti Organometallici (ICCOM) Bari Section, Consiglio Nazionale delle Ricerche, Via Orabona 4, 70126, Bari, Italy.; Fusco C; CNR - Istituto di Chimica dei Composti Organometallici (ICCOM) Bari Section, Consiglio Nazionale delle Ricerche, Via Orabona 4, 70126, Bari, Italy.; Nacci A; Chemistry Department, Università degli Studi di Bari Aldo Moro, Via Orabona 4, 70126, Bari, Italy.; CNR - Istituto di Chimica dei Composti Organometallici (ICCOM) Bari Section, Consiglio Nazionale delle Ricerche, Via Orabona 4, 70126, Bari, Italy.; Monopoli A; Chemistry Department, Università degli Studi di Bari Aldo Moro, Via Orabona 4, 70126, Bari, Italy.; CNR - Istituto di Chimica dei Composti Organometallici (ICCOM) Bari Section, Consiglio Nazionale delle Ricerche, Via Orabona 4, 70126, Bari, Italy.
Source
Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 9513783 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-3765 (Electronic) Linking ISSN: 09476539 NLM ISO Abbreviation: Chemistry Subsets: MEDLINE
Subject
Language
English
Abstract
A novel Pd-catalysed oxidative coupling between benzoic acids and vinylarenes or acrylates to furnish isocoumarins and phthalides is reported. The reaction proceeds smoothly in molten tetrabutylammonium acetate via a selective C-H bond activation, with very low percentage of ligand-free palladium acetate as the catalyst, under atmospheric pressure of oxygen. Sub-stoichiometric amount of copper acetate is also required as a reoxidant for the palladium.
(© 2022 The Authors. Chemistry - A European Journal published by Wiley-VCH GmbH.)
(© 2022 The Authors. Chemistry - A European Journal published by Wiley-VCH GmbH.)