학술논문
Initiation and duration of selective serotonin reuptake inhibitor prescribing over time: UK cohort study.
Document Type
Academic Journal
Author
McCrea RL; Rachel L. McCrea, PhD, Cormac J. Sammon, PhD, Irwin Nazareth, PhD, FRCGP, Department of Primary Care and Population Health, University College London, London, UK; Irene Petersen, PhD, Department of Primary Care and Population Health, University College London, London, UK, and Department of Clinical Epidemiology, Aarhus University, Aarhus, Denmark.; Sammon CJ; Rachel L. McCrea, PhD, Cormac J. Sammon, PhD, Irwin Nazareth, PhD, FRCGP, Department of Primary Care and Population Health, University College London, London, UK; Irene Petersen, PhD, Department of Primary Care and Population Health, University College London, London, UK, and Department of Clinical Epidemiology, Aarhus University, Aarhus, Denmark.; Nazareth I; Rachel L. McCrea, PhD, Cormac J. Sammon, PhD, Irwin Nazareth, PhD, FRCGP, Department of Primary Care and Population Health, University College London, London, UK; Irene Petersen, PhD, Department of Primary Care and Population Health, University College London, London, UK, and Department of Clinical Epidemiology, Aarhus University, Aarhus, Denmark.; Petersen I; Rachel L. McCrea, PhD, Cormac J. Sammon, PhD, Irwin Nazareth, PhD, FRCGP, Department of Primary Care and Population Health, University College London, London, UK; Irene Petersen, PhD, Department of Primary Care and Population Health, University College London, London, UK, and Department of Clinical Epidemiology, Aarhus University, Aarhus, Denmark i.petersen@ucl.ac.uk.
Source
Publisher: Cambridge University Press Country of Publication: England NLM ID: 0342367 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1472-1465 (Electronic) Linking ISSN: 00071250 NLM ISO Abbreviation: Br J Psychiatry Subsets: MEDLINE
Subject
Language
English
Abstract
Background: Recent media reports have focused on the large increase in antidepressants dispensed in England. We investigated this, focusing on selective serotonin reuptake inhibitors (SSRIs).
Aims: To examine the rate of initiation of SSRIs over time and changes over time in the duration of prescribing episodes.
Method: We estimated initiation and duration of SSRI prescribing from 7 025 802 individuals aged over 18 years and registered with a general practice that contributed data to The Health Improvement Network.
Results: Rates of SSRI initiation increased from 1.03 per 100 person-years in 1995 to 2.15 in 2001, but remained stable from then to 2012. The median duration of prescribing episodes increased from 112 to 169 days for episodes starting in 1995 to 2010.
Conclusions: Despite media reports describing an increasing rate of antidepressant prescribing, SSRI initiation rates have stabilised since 2001. However, our results suggest that individuals who take SSRIs are receiving treatment for longer.
(© The Royal College of Psychiatrists 2016.)
Aims: To examine the rate of initiation of SSRIs over time and changes over time in the duration of prescribing episodes.
Method: We estimated initiation and duration of SSRI prescribing from 7 025 802 individuals aged over 18 years and registered with a general practice that contributed data to The Health Improvement Network.
Results: Rates of SSRI initiation increased from 1.03 per 100 person-years in 1995 to 2.15 in 2001, but remained stable from then to 2012. The median duration of prescribing episodes increased from 112 to 169 days for episodes starting in 1995 to 2010.
Conclusions: Despite media reports describing an increasing rate of antidepressant prescribing, SSRI initiation rates have stabilised since 2001. However, our results suggest that individuals who take SSRIs are receiving treatment for longer.
(© The Royal College of Psychiatrists 2016.)