학술논문
Seeing beyond skin deep: High-resolution ultrasound in dermatology-A comprehensive review and future prospects.
Document Type
Academic Journal
Author
Liu ZF; The Alfred Hospital, Melbourne, Victoria, Australia.; Chew CY; The Alfred Hospital, Melbourne, Victoria, Australia.; Faculty of Medicine, Monash University, Melbourne, Victoria, Australia.; Honavar S; Faculty of Medicine, Monash University, Melbourne, Victoria, Australia.; Maxwell A; Royal Melbourne Hospital, Melbourne, Victoria, Australia.; Sylivris A; Royal Melbourne Hospital, Melbourne, Victoria, Australia.; Sheridan A; The Alfred Hospital, Melbourne, Victoria, Australia.; Specialist Dermatology, Surgery & Laser, Melbourne, Victoria, Australia.; Specialist Dermatology, Surgery & Laser, Adelaide, South Australia, Australia.
Source
Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 9216037 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1468-3083 (Electronic) Linking ISSN: 09269959 NLM ISO Abbreviation: J Eur Acad Dermatol Venereol Subsets: MEDLINE
Subject
Language
English
Abstract
High-resolution ultrasound (HRUS), operating at frequencies of 20-25 MHz, is a non-invasive imaging tool that offers dermatologists the ability to visualize structures beneath the skin surface. The objective of this review is to present a comprehensive overview of HRUS applications, emphasising its utility in diagnosing, characterising and managing various dermatological conditions. We undertook a comprehensive literature review on the dermatological application of HRUS across Medline, Embase and Cochrane Library databases, while also incorporating our own clinical experience of over 16 years with the tool. In normal skin, the epidermis and dermis are hyperechoic, and the subcutaneous layer is hypoechoic. Basal cell carcinomas appear hypoechoic with irregular margins, while the presence of hyperechoic inclusion bodies suggests aggressive pathology. Squamous cell carcinomas pose challenges due to acoustic shadow artefacts from the thickened stratum corneum. Melanomas are homogenous hypoechoic lesions, with HRUS used to accurately predict Breslow thickness. HRUS provides dermatologists with a valuable adjunct to traditional clinical examination. Future advancement in image resolution and the standardisation of diagnostic parameters may further expand its utility.
(© 2024 European Academy of Dermatology and Venereology.)
(© 2024 European Academy of Dermatology and Venereology.)