학술논문
Acute aortic thrombosis in patients receiving cisplatin-based chemotherapy.
Document Type
Academic Journal
Author
Fernandes DD; University of Ottawa, Department of Diagnostic Imaging, The Ottawa Hospital-General Campus, Ottawa, ON.; Louzada ML; Souza CA; Matzinger F
Source
Publisher: MDPI Country of Publication: Switzerland NLM ID: 9502503 Publication Model: Print Cited Medium: Internet ISSN: 1718-7729 (Electronic) Linking ISSN: 11980052 NLM ISO Abbreviation: Curr Oncol Subsets: PubMed not MEDLINE
Subject
Language
English
Abstract
The increased risk of thrombosis in patients with active cancer has multiple causes. Acute thrombosis of the aorta is an exceedingly rare but potentially devastating complication in patients with cancer receiving cisplatin-based chemotherapy. Prompt diagnosis and definitive treatment are imperative to decrease morbidity and mortality. Early diagnosis is difficult because initial presentation is often nonspecific, requiring a high degree of clinical suspicion. We report 4 cases of acute thrombosis of the abdominal aorta in patients with cancer receiving cisplatin-based chemotherapy. We review the clinical aspects, recommended investigation, and treatment of this potentially fatal complication.