학술논문
Radiologic patterns of distant organ metastasis in advanced breast cancer patients: Prospective review of computed tomography images.
Document Type
Academic Journal
Author
Jimah BB; Department of Medical Imaging, University of Cape Coast, Cape Coast, Ghana.; Amoako E; Yemaachi Biotech, Accra, Ghana.; Ofori EO; Department of Surgery, Cape Coast Teaching Hospital, Cape Coast, Ghana.; Akakpo PK; Department of Pathology, University of Cape Coast, Cape Coast, Ghana.; Aniakwo LA; Department of Surgery, Cape Coast Teaching Hospital, Cape Coast, Ghana.; Ulzen-Appiah K; Department of Pathology, Cape Coast Teaching Hospital, Cape Coast, Ghana.; Imbeah EG; ACT Pathology Services, Cape Coast, Ghana.; Morna MT; Department of Surgery, University of Cape Coast, Cape Coast, Ghana.; Koggoh P; Department of Surgery, Cape Coast Teaching Hospital, Cape Coast, Ghana.; Akligoh H; Yemaachi Biotech, Accra, Ghana.; Tackie R; Yemaachi Biotech, Accra, Ghana.; Manu A; Yemaachi Biotech, Accra, Ghana.; Paemka L; Yemaachi Biotech, Accra, Ghana.; Sarkodie BD; Department of Radiology, School of Medicine and Dentistry, University of Ghana, Accra, Ghana.; Offei AK; Department of Surgery, Korle Bu Teaching Hospital, Accra, Ghana.; Hutchful D; Yemaachi Biotech, Accra, Ghana.; Ngoi J; Yemaachi Biotech, Accra, Ghana.; Bediako Y; Yemaachi Biotech, Accra, Ghana.; Rahman GA; Department of Surgery, University of Cape Coast, Cape Coast, Ghana.
Source
Publisher: John Wiley & Sons, Inc Country of Publication: United States NLM ID: 101747728 Publication Model: Print Cited Medium: Internet ISSN: 2573-8348 (Electronic) Linking ISSN: 25738348 NLM ISO Abbreviation: Cancer Rep (Hoboken) Subsets: MEDLINE
Subject
Language
English
Abstract
Background: Breast cancer (BC) metastases to the abdomen and pelvis affect the liver, mesentery, retroperitoneum, peritoneum, bladder, kidney, ovary, and uterus. The study documented the radiological pattern and features of the chest, bone, abdominal and pelvic (AP) metastases among advanced BC patients.
Aim: The aim is to document the radiological pattern and features of breast cancer metastasis in the chest, abdomen, pelvis and bones.
Materials and Results: Chest, abdominal, and pelvic computed tomography scan images of 36 patients with advanced BC were collated from Cape Coast Teaching Hospital and RAAJ Diagnostics. The images were prospectively assessed for metastasis to the organs of the chest, AP soft tissues, and bones. Radiologic features of metastasis of the lungs, liver, lymph nodes (LNs), and bones were documented. Patients' demographics, clinical data, and histopathology reports were also collected. The data were captured using UVOSYO and exported to Microsoft Excel templates. The data obtained were descriptively analyzed. Only 2.8% of BCs exhibited metaplastic BC, whereas 97.2% had invasive ductal BC. Triple-negative cases were 55.6%. Of 36 patients, 31 (86.1%), 21 (58.3%), and 14(38.8%) were diagnosed of chest, AP, and bone tissues metastasis, respectively. LN involvement was reported in 26 (72.2%) patients. Majority, 21 (58.3%) were diagnosed of multiple sites metastasis with 15 (41.7%) showing single site. Lungs (77.4%, 24/31) and liver (47.6%, 10/21) were the most affected distant organs. Most bone metastases were lytic lesions (92.9%, 13/14) with the vertebrae (85.7%, 12/14) been the most affected.
Conclusion: According to the study, advanced BC patients have a higher-than-average radiologic incidence of lung, liver, bone, and LN metastases.
(© 2024 The Authors. Cancer Reports published by Wiley Periodicals LLC.)
Aim: The aim is to document the radiological pattern and features of breast cancer metastasis in the chest, abdomen, pelvis and bones.
Materials and Results: Chest, abdominal, and pelvic computed tomography scan images of 36 patients with advanced BC were collated from Cape Coast Teaching Hospital and RAAJ Diagnostics. The images were prospectively assessed for metastasis to the organs of the chest, AP soft tissues, and bones. Radiologic features of metastasis of the lungs, liver, lymph nodes (LNs), and bones were documented. Patients' demographics, clinical data, and histopathology reports were also collected. The data were captured using UVOSYO and exported to Microsoft Excel templates. The data obtained were descriptively analyzed. Only 2.8% of BCs exhibited metaplastic BC, whereas 97.2% had invasive ductal BC. Triple-negative cases were 55.6%. Of 36 patients, 31 (86.1%), 21 (58.3%), and 14(38.8%) were diagnosed of chest, AP, and bone tissues metastasis, respectively. LN involvement was reported in 26 (72.2%) patients. Majority, 21 (58.3%) were diagnosed of multiple sites metastasis with 15 (41.7%) showing single site. Lungs (77.4%, 24/31) and liver (47.6%, 10/21) were the most affected distant organs. Most bone metastases were lytic lesions (92.9%, 13/14) with the vertebrae (85.7%, 12/14) been the most affected.
Conclusion: According to the study, advanced BC patients have a higher-than-average radiologic incidence of lung, liver, bone, and LN metastases.
(© 2024 The Authors. Cancer Reports published by Wiley Periodicals LLC.)