학술논문
A social cost-benefit analysis of two One Health interventions to prevent toxoplasmosis.
Document Type
Academic Journal
Author
Suijkerbuijk AWM; National Institute for Public Health and the Environment, Bilthoven, the Netherlands.; Over EAB; National Institute for Public Health and the Environment, Bilthoven, the Netherlands.; Opsteegh M; National Institute for Public Health and the Environment, Bilthoven, the Netherlands.; Deng H; National Institute for Public Health and the Environment, Bilthoven, the Netherlands.; Gils PFV; National Institute for Public Health and the Environment, Bilthoven, the Netherlands.; Bonačić Marinović AA; National Institute for Public Health and the Environment, Bilthoven, the Netherlands.; Lambooij M; National Institute for Public Health and the Environment, Bilthoven, the Netherlands.; Polder JJ; National Institute for Public Health and the Environment, Bilthoven, the Netherlands.; Tilburg University, Tranzo, School of Social and Behavioral Sciences, Tilburg, the Netherlands.; Feenstra TL; National Institute for Public Health and the Environment, Bilthoven, the Netherlands.; University of Groningen, Department of epidemiology, Groningen, the Netherlands.; Giessen JWBV; National Institute for Public Health and the Environment, Bilthoven, the Netherlands.; Wit GA; National Institute for Public Health and the Environment, Bilthoven, the Netherlands.; University Medical Center Utrecht, Julius Center for Health Sciences and Primary Care, Utrecht, the Netherlands.; Mangen MJ; National Institute for Public Health and the Environment, Bilthoven, the Netherlands.
Source
Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE
Subject
Language
English
Abstract
In the Netherlands, toxoplasmosis ranks second in disease burden among foodborne pathogens with an estimated health loss of 1,900 Disability Adjusted Life Years and a cost-of-illness estimated at €45 million annually. Therefore, effective and preferably cost-effective preventive interventions are warranted. Freezing meat intended for raw or undercooked consumption and improving biosecurity in pig farms are promising interventions to prevent Toxoplasma gondii infections in humans. Putting these interventions into practice would expectedly reduce the number of infections; however, the net benefits for society are unknown. Stakeholders bearing the costs for these interventions will not necessary coincide with the ones having the benefits. We performed a Social Cost-Benefit Analysis to evaluate the net value of two potential interventions for the Dutch society. We assessed the costs and benefits of the two interventions and compared them with the current practice of education, especially during pregnancy. A 'minimum scenario' and a 'maximum scenario' was assumed, using input parameters with least benefits to society and input parameters with most benefits to society, respectively. For both interventions, we performed different scenario analyses. The freezing meat intervention was far more effective than the biosecurity intervention. Despite high freezing costs, freezing two meat products: steak tartare and mutton leg yielded net social benefits in both the minimum and maximum scenario, ranging from €10.6 million to €31 million for steak tartare and €0.6 million to €1.5 million for mutton leg. The biosecurity intervention would result in net costs in all scenarios ranging from €1 million to €2.5 million, due to high intervention costs and limited benefits. From a public health perspective (i.e. reducing the burden of toxoplasmosis) and the societal perspective (i.e. a net benefit for the Dutch society) freezing steak tartare and leg of mutton is to be considered.
Competing Interests: The authors have declared that no competing interests exist.
Competing Interests: The authors have declared that no competing interests exist.