학술논문
4D Flow Versus 2D Phase Contrast MRI in Populations With Bi- and Tricuspid Aortic Valves.
Document Type
Academic Journal
Author
Hautanen S; Institute of Clinical Medicine, Faculty of Health Sciences, University of Eastern Finland, Kuopio, Finland.; Department of Heart and Thoracic Surgery, Kuopio University Hospital, Heart Center, Kuopio, Finland.; Kiljander T; Department of Cardiology, Tampere University Hospital, Heart Hospital NOVA, Jyväskylä, Finland; ext-teemu.kiljander@ksshp.fi.; Department of Cardiology, Central Finland Central Hospital, Jyväskylä, Finland.; Korpela T; Institute of Clinical Medicine, Faculty of Health Sciences, University of Eastern Finland, Kuopio, Finland.; Department of Heart and Thoracic Surgery, Kuopio University Hospital, Heart Center, Kuopio, Finland.; Saari P; Diagnostic Imaging Center, Kuopio University Hospital, Kuopio, Finland.; Kokkonen J; Department of Cardiology, Central Finland Central Hospital, Jyväskylä, Finland.; Mustonen P; Department of Cardiology, Central Finland Central Hospital, Jyväskylä, Finland.; Sillanmäki S; Diagnostic Imaging Center, Kuopio University Hospital, Kuopio, Finland.; Ylä-Herttuala E; Clinical Radiology, Kuopio University Hospital, Clinical Imaging Center, Kuopio, Finland.; Husso M; Clinical Radiology, Kuopio University Hospital, Clinical Imaging Center, Kuopio, Finland.; Hedman M; Institute of Clinical Medicine, Faculty of Health Sciences, University of Eastern Finland, Kuopio, Finland.; Department of Heart and Thoracic Surgery, Kuopio University Hospital, Heart Center, Kuopio, Finland.; Clinical Radiology, Kuopio University Hospital, Clinical Imaging Center, Kuopio, Finland.; Kauhanen P; Clinical Radiology, Kuopio University Hospital, Clinical Imaging Center, Kuopio, Finland.
Source
Publisher: International Institute of Anticancer Research Country of Publication: Greece NLM ID: 8806809 Publication Model: Print Cited Medium: Internet ISSN: 1791-7549 (Electronic) Linking ISSN: 0258851X NLM ISO Abbreviation: In Vivo Subsets: MEDLINE
Subject
Language
English
Abstract
Aim: To compare 4D flow magnetic resonance imaging (MRI) and 2D phase contrast (PC) MRI when evaluating bicuspid (BAV) and tricuspid (TAV) aortic valves.
Materials and Methods: A total of 83 subjects (35 BAV, 48 TAV) were explored with 4D flow and 2D PC MRI. Systolic peak velocity, peak flow and regurgitation fraction were analysed at two pre-defined aortic levels (aortic root, mid-tubular). Furthermore, the two methods of 4D flow analysis (Heart and Artery) were compared.
Results: Correlation between the 2D PC MRI and 4D flow MRI derived parameters ranged from moderate (R=0.58) to high (R=0.90). 4D flow MRI yielded significantly higher peak velocities in the tubular aorta in both groups. Regarding the aortic root, peak velocities were significantly higher in the TAV group with 4D flow MRI, but in the BAV group 4D flow MRI yielded non-significantly lower values. Findings on peak flow differences between the two modalities followed the same pattern as the differences in peak velocities. 4D flow MRI derived regurgitation fraction values were lower in both locations in both groups. Interobserver agreement for different 4D flow MRI acquired parameters varied from poor (ICC=0.07) to excellent (ICC=1.0) in the aortic root, and it was excellent in the tubular aorta (ICC=0.8-1.0).
Conclusion: 4D flow MRI seems to be accurate in comparison to 2D PC MRI in normal aortic valves and in BAV with mild to moderate stenosis. However, the varying interobserver reproducibility and impaired accuracy at higher flow velocities should be taken into account in clinical practice when using the 4D flow method.
(Copyright © 2023, International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.)
Materials and Methods: A total of 83 subjects (35 BAV, 48 TAV) were explored with 4D flow and 2D PC MRI. Systolic peak velocity, peak flow and regurgitation fraction were analysed at two pre-defined aortic levels (aortic root, mid-tubular). Furthermore, the two methods of 4D flow analysis (Heart and Artery) were compared.
Results: Correlation between the 2D PC MRI and 4D flow MRI derived parameters ranged from moderate (R=0.58) to high (R=0.90). 4D flow MRI yielded significantly higher peak velocities in the tubular aorta in both groups. Regarding the aortic root, peak velocities were significantly higher in the TAV group with 4D flow MRI, but in the BAV group 4D flow MRI yielded non-significantly lower values. Findings on peak flow differences between the two modalities followed the same pattern as the differences in peak velocities. 4D flow MRI derived regurgitation fraction values were lower in both locations in both groups. Interobserver agreement for different 4D flow MRI acquired parameters varied from poor (ICC=0.07) to excellent (ICC=1.0) in the aortic root, and it was excellent in the tubular aorta (ICC=0.8-1.0).
Conclusion: 4D flow MRI seems to be accurate in comparison to 2D PC MRI in normal aortic valves and in BAV with mild to moderate stenosis. However, the varying interobserver reproducibility and impaired accuracy at higher flow velocities should be taken into account in clinical practice when using the 4D flow method.
(Copyright © 2023, International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.)