학술논문
Associations of dietary intake and longitudinal measures of per- and polyfluoroalkyl substances (PFAS) in predominantly Hispanic young Adults: A multicohort study.
Document Type
Academic Journal
Author
Hampson HE; Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA, the United States of America.; Costello E; Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA, the United States of America.; Walker DI; Department of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, NY, the United States of America.; Wang H; Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA, the United States of America.; Baumert BO; Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA, the United States of America.; Valvi D; Department of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, NY, the United States of America.; Rock S; Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA, the United States of America.; Jones DP; Clinical Biomarkers Laboratory, Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Emory University, Atlanta, GA, the United States of America.; Goran MI; Department of Pediatrics, Keck School of Medicine, USC and The Saban Research Institute, Children's Hospital Los Angeles, Los Angeles, CA 90027, the United States of America.; Gilliland FD; Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA, the United States of America.; Conti DV; Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA, the United States of America.; Alderete TL; Department of Integrative Physiology, University of Colorado Boulder, Boulder, CO, the United States of America.; Chen Z; Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA, the United States of America.; Chatzi L; Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA, the United States of America.; Goodrich JA; Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA, the United States of America. Electronic address: jagoodri@usc.edu.
Source
Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 7807270 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-6750 (Electronic) Linking ISSN: 01604120 NLM ISO Abbreviation: Environ Int Subsets: MEDLINE
Subject
Language
English
Abstract
Background: Per- and polyfluoroalkyl substances (PFAS) are pollutants linked to adverse health effects. Diet is an important source of PFAS exposure, yet it is unknown how diet impacts longitudinal PFAS levels.
Objective: To determine if dietary intake and food sources were associated with changes in blood PFAS concentrations among Hispanic young adults at risk of metabolic diseases.
Methods: Predominantly Hispanic young adults from the Children's Health Study who underwent two visits (CHS; n = 123) and young adults from NHANES 2013-2018 who underwent one visit (n = 604) were included. Dietary data at baseline was collected using two 24-hour dietary recalls to measure individual foods and where foods were prepared/consumed (home/restaurant/fast-food). PFAS were measured in blood at both visits in CHS and cross-sectionally in NHANES. In CHS, multiple linear regression assessed associations of baseline diet with longitudinal PFAS; in NHANES, linear regression was used.
Results: In CHS, all PFAS except PFDA decreased across visits (all p < 0.05). In CHS, A 1-serving higher tea intake was associated with 24.8 %, 16.17 %, and 12.6 % higher PFHxS, PFHpS, and PFNA at follow-up, respectively (all p < 0.05). A 1-serving higher pork intake was associated with 13.4 % higher PFOA at follow-up (p < 0.05). Associations were similar in NHANES, including unsweetened tea, hot dogs, and processed meats. For food sources, in CHS each 200-gram increase in home-prepared food was associated with 0.90 % and 1.6 % lower PFOS at baseline and follow-up, respectively, and in NHANES was associated with 0.9 % lower PFDA (all p < 0.05).
Conclusion: Results suggest that beverage consumption habits and food preparation are associated with differences in PFAS levels in young adults. This highlights the importance of diet in determining PFAS exposure and the necessity of public monitoring of foods and beverages for PFAS contamination.
Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2024 The Authors. Published by Elsevier Ltd.. All rights reserved.)
Objective: To determine if dietary intake and food sources were associated with changes in blood PFAS concentrations among Hispanic young adults at risk of metabolic diseases.
Methods: Predominantly Hispanic young adults from the Children's Health Study who underwent two visits (CHS; n = 123) and young adults from NHANES 2013-2018 who underwent one visit (n = 604) were included. Dietary data at baseline was collected using two 24-hour dietary recalls to measure individual foods and where foods were prepared/consumed (home/restaurant/fast-food). PFAS were measured in blood at both visits in CHS and cross-sectionally in NHANES. In CHS, multiple linear regression assessed associations of baseline diet with longitudinal PFAS; in NHANES, linear regression was used.
Results: In CHS, all PFAS except PFDA decreased across visits (all p < 0.05). In CHS, A 1-serving higher tea intake was associated with 24.8 %, 16.17 %, and 12.6 % higher PFHxS, PFHpS, and PFNA at follow-up, respectively (all p < 0.05). A 1-serving higher pork intake was associated with 13.4 % higher PFOA at follow-up (p < 0.05). Associations were similar in NHANES, including unsweetened tea, hot dogs, and processed meats. For food sources, in CHS each 200-gram increase in home-prepared food was associated with 0.90 % and 1.6 % lower PFOS at baseline and follow-up, respectively, and in NHANES was associated with 0.9 % lower PFDA (all p < 0.05).
Conclusion: Results suggest that beverage consumption habits and food preparation are associated with differences in PFAS levels in young adults. This highlights the importance of diet in determining PFAS exposure and the necessity of public monitoring of foods and beverages for PFAS contamination.
Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2024 The Authors. Published by Elsevier Ltd.. All rights reserved.)