학술논문
Carotid Stenosis and Stroke: Historical Perspectives Leading to Current Challenges.
Document Type
Academic Journal
Author
Pelz DM; Department of Medical Imaging, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.; Fox AJ; University of Toronto, Toronto, ON, Canada.; Spence JD; Neurology and Clinical Pharmacology, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.; Stroke Prevention and Atherosclerosis Research Centre, Robarts Research Institute, London, ON, Canada.; Lownie SP; Division of Neurosurgery, Department of Surgery, Dalhousie University, Halifax, NS, Canada.; Schulich School of Medicine and Dentistry, Western University, Halifax, NS, Canada.
Source
Publisher: published by Cambridge University Press for the Canadian Neurological Sciences Federation Country of Publication: England NLM ID: 0415227 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 0317-1671 (Print) Linking ISSN: 03171671 NLM ISO Abbreviation: Can J Neurol Sci Subsets: MEDLINE
Subject
Language
English
ISSN
0317-1671
Abstract
The carotid artery is unique; it is the only vessel to bifurcate into a bulb larger than itself. The history of its anatomic description, understanding of its pathophysiology and evolution of its imaging are relevant to current controversies regarding measurement of stenosis, surgical/endovascular therapies and medical management of carotid stenosis in stroke prevention. Treatment decisions on millions of symptomatic and asymptomatic patients are routinely based on information from clinical trials from over 30 years ago. This article briefly summarizes the highlights of past research in key areas and discuss how they led to current challenges of diagnosis and treatment.