학술논문
Surgical and Pharmacological Management of Periprosthetic Atypical Femoral Fractures: A Narrative Literature Review.
Document Type
Academic Journal
Author
Troiano E; Department of Medicine Surgery and Neurosciences, University of Siena, Siena, Italy.; Section of Orthopedics, Azienda Ospedaliero-Universitaria Senese, Siena, Italy.; Giacché T; Department of Medicine Surgery and Neurosciences, University of Siena, Siena, Italy.; Section of Orthopedics, Azienda Ospedaliero-Universitaria Senese, Siena, Italy.; Facchini A; Department of Medicine Surgery and Neurosciences, University of Siena, Siena, Italy.; Section of Orthopedics, Azienda Ospedaliero-Universitaria Senese, Siena, Italy.; Orlandi NC; Department of Medicine Surgery and Neurosciences, University of Siena, Siena, Italy.; Section of Orthopedics, Azienda Ospedaliero-Universitaria Senese, Siena, Italy.; Cacioppo M; Department of Medicine Surgery and Neurosciences, University of Siena, Siena, Italy.; Section of Orthopedics, Azienda Ospedaliero-Universitaria Senese, Siena, Italy.; Saviori M; Department of Medicine Surgery and Neurosciences, University of Siena, Siena, Italy.; Section of Orthopedics, Azienda Ospedaliero-Universitaria Senese, Siena, Italy.; Bottai V; Second Clinic of Orthopedic and Traumatology, University of Pisa, Pisa, Italy.; Muratori F; Section of Orthopedic Oncology and Reconstructive Surgery, Azienda Ospedaliero-Universitaria Careggi, Firenze, Italy.; Mondanelli N; Department of Medicine Surgery and Neurosciences, University of Siena, Siena, Italy.; Section of Orthopedics, Azienda Ospedaliero-Universitaria Senese, Siena, Italy.; Giannotti S; Department of Medicine Surgery and Neurosciences, University of Siena, Siena, Italy.; Section of Orthopedics, Azienda Ospedaliero-Universitaria Senese, Siena, Italy.
Source
Publisher: Sage Publications Country of Publication: United States NLM ID: 101558150 Publication Model: eCollection Cited Medium: Print ISSN: 2151-4585 (Print) Linking ISSN: 21514585 NLM ISO Abbreviation: Geriatr Orthop Surg Rehabil Subsets: PubMed not MEDLINE
Subject
Language
English
ISSN
2151-4585
Abstract
Introduction: An increasing number of patients is annually undergoing total hip arthroplasty (THA), and a significant proportion of these patients are elderly and consequently at a higher risk of complications because of age, osteoporosis, and medical comorbidities. Periprosthetic femoral fractures (PFFs) are one of the worst complications of THA associated with high rates of unfavorable prognosis. Besides, in the last decade, a new independent disease entity called "atypical femoral fracture" (AFF) has been identified and defined by the American Society for Bone and Mineral Research (ASBMR) task force. Some PFFs present clinical history and radiographic aspect consistent with an AFF, meeting the ASBMR criteria for the diagnosis of AFF except that PFFs by themselves are an exclusion criterion for AFF. However, there is an increasing number of published studies suggesting that periprosthetic atypical femoral fractures (PAFFs) exist and should not be excluded by definition.
Significance: Nowadays, although there is an increasing interest in PAFFs, there are still very few studies published on the topic and a lack of consensus regarding their treatment. This narrative literature review aims to introduce this new emerging topic to a wider readership describing the characteristics of PAFFs and the state-of-the-art in their management.
Conclusions: Many authors agree that PAFFs should be considered as a subgroup of PFFs that have atypical characteristics; they also show a significant correlation with prolonged bisphosphonate use. A correct diagnosis is paramount for proper treatment of the disease that requires both surgical and medical actions to be taken.
Competing Interests: Declaration of Conflicting Interests: The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
(© The Author(s) 2022.)
Significance: Nowadays, although there is an increasing interest in PAFFs, there are still very few studies published on the topic and a lack of consensus regarding their treatment. This narrative literature review aims to introduce this new emerging topic to a wider readership describing the characteristics of PAFFs and the state-of-the-art in their management.
Conclusions: Many authors agree that PAFFs should be considered as a subgroup of PFFs that have atypical characteristics; they also show a significant correlation with prolonged bisphosphonate use. A correct diagnosis is paramount for proper treatment of the disease that requires both surgical and medical actions to be taken.
Competing Interests: Declaration of Conflicting Interests: The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
(© The Author(s) 2022.)