학술논문

Glycemic and lipid control in patients with diabetes at time of myocardial infarction.
Document Type
Academic Journal
Author
Lacqua C; Pharmacy Department, Dijon Bourgogne University Hospital, 21000 Dijon, France.; Adam H; Pharmacy Department, Dijon Bourgogne University Hospital, 21000 Dijon, France.; Zeller M; Cardiology Department, Dijon Bourgogne University Hospital, PEC2, EA 7460, 21000 Dijon, France.; Vadot L; Pharmacy Department, Dijon Bourgogne University Hospital, 21000 Dijon, France.; Bichat F; Cardiology Department, Dijon Bourgogne University Hospital, 21000 Dijon, France.; Maza M; Cardiology Department, Dijon Bourgogne University Hospital, 21000 Dijon, France.; Cottin Y; Cardiology Department, Dijon Bourgogne University Hospital, PEC2, EA 7460, 21000 Dijon, France.; Boulin M; Department of Pharmacy, University Hospital and EPICAD LNC UMR 1231, University of Burgundy & Franche Comte, Dijon, France. Electronic address: mathieu.boulin@chu.dijon.fr.
Source
Publisher: Elsevier Masson Editeur Country of Publication: France NLM ID: 2985176R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 0003-4509 (Print) Linking ISSN: 00034509 NLM ISO Abbreviation: Ann Pharm Fr Subsets: MEDLINE
Subject
Language
English
ISSN
0003-4509
Abstract
Objective: Cardiovascular risk is increased in patients with diabetes. Little is known about glycemic and lipid control in patients with diabetes. We aimed to assess glycemic and lipid controls in patients with diabetes at time of their myocardial infarction.
Method: All known patients with type 2 diabetes consecutively admitted for a myocardial infarction in our coronary care unit between March 1 st and December 31 st , 2021 were included in this retrospective study. Glycemic and lipid control was assessed through individualized target of glycated haemoglobin (HbA 1c ) and low-density lipoprotein cholesterol (LDL-c), respectively. At admission, the comprehensive list of chronic medications was obtained through medication reconciliation.
Results: This study included 112 patients with a median age of 72 years. Most of patients had an individualized target of HbA 1c and LDL-c of 7.0% (67%) and 0.55g/L (96%), respectively. The rate of uncontrolled patients for HbA 1c and LDL-c and both was 46%, 90%, and 42% respectively. The rate of patients with non-optimal glucose- and lipid-lowering medications in uncontrolled patients was 63% and 87%, respectively. The rate of inappropriate glucose- and lipid-lowering medications was 73% and 91%, respectively.
Conclusion: We highlighted the poor glycemic and lipid control in high-risk CV patients. There is an urgent need to develop multidisciplinary approaches to optimize CV risk factors control to reduce myocardial infarction and strokes.
(Copyright © 2024. Published by Elsevier Masson SAS.)