학술논문
Double inversion recovery MR sequence for the detection of subacute subarachnoid hemorrhage.
Document Type
Academic Journal
Author
Hodel J; From the Departments of Neuroradiology (J.H., B.D., E.K., J.-P.P., X.L.) Department of Radiology (J.H., M.Z.), Hôpital Saint Joseph, Paris, France Jerome.hodel@gmail.com.; Aboukais R; Neurosurgery (R.A., J.-P.L.), Hôpital Roger Salengro, Lille, France.; Dutouquet B; From the Departments of Neuroradiology (J.H., B.D., E.K., J.-P.P., X.L.).; Kalsoum E; From the Departments of Neuroradiology (J.H., B.D., E.K., J.-P.P., X.L.).; Benadjaoud MA; Institut National De La Santé et De La Recherche Médicale (M.A.B.), Centre for Research in Epidemiology and Population Health, Villejuif, France.; Chechin D; Philips Medical Systems (D.C.), Suresnes, France.; Zins M; Department of Radiology (J.H., M.Z.), Hôpital Saint Joseph, Paris, France.; Rahmouni A; Department of Radiology (A.R., A.L.), Centre Hospitalier Universitaire, Henri Mondor, Créteil, France.; Luciani A; Department of Radiology (A.R., A.L.), Centre Hospitalier Universitaire, Henri Mondor, Créteil, France.; Pruvo JP; From the Departments of Neuroradiology (J.H., B.D., E.K., J.-P.P., X.L.).; Lejeune JP; Neurosurgery (R.A., J.-P.L.), Hôpital Roger Salengro, Lille, France.; Leclerc X; From the Departments of Neuroradiology (J.H., B.D., E.K., J.-P.P., X.L.).
Source
Publisher: American Society of Neuroradiology Country of Publication: United States NLM ID: 8003708 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1936-959X (Electronic) Linking ISSN: 01956108 NLM ISO Abbreviation: AJNR Am J Neuroradiol Subsets: MEDLINE
Subject
Language
English
Abstract
Background and Purpose: The diagnosis of subacute subarachnoid hemorrhage is important because rebleeding may occur with subsequent life-threatening hemorrhage. Our aim was to determine the sensitivity of the 3D double inversion recovery sequence compared with CT, 2D and 3D FLAIR, 2D T2*, and 3D SWI sequences for the detection of subacute SAH.
Materials and Methods: This prospective study included 25 patients with a CT-proved acute SAH. Brain imaging was repeated between days 14 and 16 (mean, 14.75 days) after clinical onset and included MR imaging (2D and 3D FLAIR, 2D T2*, SWI, and 3D double inversion recovery) after CT (median delay, 3 hours; range, 2-5 hours). A control group of 20 healthy volunteers was used for comparison. MR images and CT scans were analyzed independently in a randomized order by 3 blinded readers. For each subject, the presence or absence of hemorrhage was assessed in 4 subarachnoid areas (basal cisterns, Sylvian fissures, interhemispheric fissure, and convexity) and in brain ventricles. The diagnosis of subacute SAH was defined by the presence of at least 1 subarachnoid area with hemorrhage.
Results: For the diagnosis of subacute SAH, the double inversion recovery sequence had a higher sensitivity compared with CT (P < .001), 2D FLAIR (P = .005), T2* (P = .02), SWI, and 3D FLAIR (P = .03) sequences. Hemorrhage was present for all patients in the interhemispheric fissure on double inversion recovery images, while no signal abnormality was noted in healthy volunteers. Interobserver agreement was excellent with double inversion recovery.
Conclusions: Our study showed that the double inversion recovery sequence has a higher sensitivity for the detection of subacute SAH than CT, 2D or 3D FLAIR, 2D T2*, and SWI.
(© 2015 by American Journal of Neuroradiology.)
Materials and Methods: This prospective study included 25 patients with a CT-proved acute SAH. Brain imaging was repeated between days 14 and 16 (mean, 14.75 days) after clinical onset and included MR imaging (2D and 3D FLAIR, 2D T2*, SWI, and 3D double inversion recovery) after CT (median delay, 3 hours; range, 2-5 hours). A control group of 20 healthy volunteers was used for comparison. MR images and CT scans were analyzed independently in a randomized order by 3 blinded readers. For each subject, the presence or absence of hemorrhage was assessed in 4 subarachnoid areas (basal cisterns, Sylvian fissures, interhemispheric fissure, and convexity) and in brain ventricles. The diagnosis of subacute SAH was defined by the presence of at least 1 subarachnoid area with hemorrhage.
Results: For the diagnosis of subacute SAH, the double inversion recovery sequence had a higher sensitivity compared with CT (P < .001), 2D FLAIR (P = .005), T2* (P = .02), SWI, and 3D FLAIR (P = .03) sequences. Hemorrhage was present for all patients in the interhemispheric fissure on double inversion recovery images, while no signal abnormality was noted in healthy volunteers. Interobserver agreement was excellent with double inversion recovery.
Conclusions: Our study showed that the double inversion recovery sequence has a higher sensitivity for the detection of subacute SAH than CT, 2D or 3D FLAIR, 2D T2*, and SWI.
(© 2015 by American Journal of Neuroradiology.)