학술논문
COVID-19 pandemic impact on cytopathology practice in the post-lockdown period: An international, multicenter study.
Document Type
Academic Journal
Author
Vigliar E; Department of Public Health, University of Naples Federico II, Naples, Italy.; Pisapia P; Department of Public Health, University of Naples Federico II, Naples, Italy.; Dello Iacovo F; Department of Advanced Biomedical Sciences, University of Naples Federico II, Naples, Italy.; Alcaraz-Mateos E; Pathology Department, Jose M. Morales Meseguer University General Hospital, Murcia, Spain.; Alì G; Department of Surgical, Medical, and Molecular Pathology and Critical Care Medicine, University of Pisa, Pisa, Italy.; Ali SZ; Division of Cytopathology, Department of Pathology, Johns Hopkins Hospital, Baltimore, Maryland.; Baloch ZW; Department of Pathology, University of Pennsylvania, Philadelphia, Pennsylvania.; Bellevicine C; Department of Public Health, University of Naples Federico II, Naples, Italy.; Bongiovanni M; Cytopathology, SYNLAB Suisse SA, Lausanne, Switzerland.; Botsun P; Anatomic Pathology, Laboratory of Pathology CSD, Kiev, Ukraine.; Bruzzese D; Department of Public Health, University of Naples Federico II, Naples, Italy.; Bubendorf L; Institute of Pathology, University Hospital Basel, Basel, Switzerland.; Büttner R; Department of Pathology, University Hospital Cologne, Cologne, Germany.; Canberk S; Medical Faculty, Institute of Molecular Pathology and Immunology, University of Porto, Porto, Portugal.; Capitanio A; Department of Pathology, Linkoping University Hospital, Linkoping, Sweden.; Casadio C; Division of Diagnostic Cytopathology, European Institute of Oncology IRCCS, Milan, Italy.; Cazacu E; Department of Morphopathology, Nicolae Testemitanu State University of Medicine and Pharmacy, Chisinau, Moldova.; Cochand-Priollet B; Department of Pathology, Cochin Hospital, Assistance Publique - Hôpitaux de Paris (APHP), University of Paris, Paris, France.; D'Amuri A; Anatomic Pathology Unit, A. Perrino Hospital, Azienda Sanitaria Locale (ASL) Brindisi, Brindisi, Italy.; Davis K; Division of Cytopathology, Department of Pathology, Johns Hopkins Hospital, Baltimore, Maryland.; Eloy C; Medical Faculty, Institute of Molecular Pathology and Immunology, University of Porto, Porto, Portugal.; Engels M; Department of Pathology, University Hospital Cologne, Cologne, Germany.; Fadda G; Section of Pathological Anatomy, Department of Human Pathology of Adult and Evolutive Age 'Gaetano Barresi', G. Martino Hospital, Messina, Italy.; Fontanini G; Department of Surgical, Medical, and Molecular Pathology and Critical Care Medicine, University of Pisa, Pisa, Italy.; Fulciniti F; Clinical Cytopathology Service, Histopathology Service, Cantonal Institute of Pathology, Locarno Cantonal Hospital, Locarno, Switzerland.; Hofman P; Laboratory of Clinical and Experimental Pathology, Hospital-Related Biobank (BB-0033-00,025), FHU OncoAge, Pasteur Hospital, Nice, France.; Iaccarino A; Department of Public Health, University of Naples Federico II, Naples, Italy.; Ieni A; Section of Pathological Anatomy, Department of Human Pathology of Adult and Evolutive Age 'Gaetano Barresi', G. Martino Hospital, Messina, Italy.; Jiang XS; Department of Pathology, Duke University Medical Center, Durham, North Carolina.; Kakudo K; Department of Pathology, Izumi City General Hospital, Izumi, Japan.; Kern I; Department of Pathology, University Clinic Golnik, Golnik, Slovenia.; Kholova I; Department of Pathology, Fimlab Laboratories, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.; Linton McDermott KM; Department of Pathology and Cytology, Queen Alexandra Hospital, Portsmouth, United Kingdom.; Liu C; Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas.; Lobo A; Department of Pathology, Kapoor Path Laboratories, Raipur, India.; Lozano MD; Department of Pathology, University Clinic of Navarra, Pamplona, Spain.; Malapelle U; Department of Public Health, University of Naples Federico II, Naples, Italy.; Maleki Z; Division of Cytopathology, Department of Pathology, Johns Hopkins Hospital, Baltimore, Maryland.; Michelow P; Department of Anatomical Pathology, University of the Witwatersrand, National Health Laboratory Service, Johannesburg, South Africa.; Mikula MW; Division of Cytopathology, Department of Pathology, Johns Hopkins Hospital, Baltimore, Maryland.; Musayev J; Department of Pathology, Baku Pathology Center, Baku, Azerbaijan.; Özgün G; Department of Pathology, Baskent University Faculty of Medicine, Ankara, Turkey.; Oznur M; Department of Pathology, Tekirdag Namik Kemal University, Suleymanpaşa/Tekirdag, Turkey.; Peiró Marqués FM; Department of Pathology, General University Hospital of Alicante, Alicante, Spain.; Poller D; Department of Pathology and Cytology, Queen Alexandra Hospital, Portsmouth, United Kingdom.; Pyzlak M; Anatomic Pathology, Center for Diagnostic Pathology, Warsaw, Poland.; Robinson B; Department of Pathology, Duke University Medical Center, Durham, North Carolina.; Rossi ED; Division of Anatomic Pathology and Histology, Catholic University of Sacred Heart-University Polyclinic Foundation 'A. Gemelli', Rome, Italy.; Roy-Chowdhuri S; Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas.; Saieg M; Department of Pathology, A. C. Camargo Cancer Center, Santa Casa Medical School, Sao Paulo, Brazil.; Savic Prince S; Institute of Pathology, University Hospital Basel, Basel, Switzerland.; Schmitt FC; Medical Faculty, Institute of Molecular Pathology and Immunology, University of Porto, Porto, Portugal.; Seguí Iváñez FJ; Department of Pathology, General University Hospital of Alicante, Alicante, Spain.; Štoos-Veić T; Department of Pathology and Cytology, University Hospital Dubrava, Zagreb, Croatia.; Sulaieva O; Anatomic Pathology, Laboratory of Pathology CSD, Kiev, Ukraine.; Sweeney BJ; Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.; Tuccari G; Section of Pathological Anatomy, Department of Human Pathology of Adult and Evolutive Age 'Gaetano Barresi', G. Martino Hospital, Messina, Italy.; van Velthuysen ML; Department of Pathology, Erasmus Medical Centre, Rotterdam, the Netherlands.; VanderLaan PA; Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts.; Vielh P; Medipath, American Hospital of Paris, Paris, France.; Viola P; North West London Pathology, Imperial College Healthcare, National Health Service Trust Charing Cross Hospital, London, United Kingdom.; Voorham QJM; Anatomic Pathology, Pathological Anatomical National Automated Archive (PALGA) Foundation, Houten, the Netherlands.; Weynand B; Department of Pathology, University Hospitals Leuven, Leuven, Belgium.; Zeppa P; Department of Medicine and Surgery, University of Salerno, Fisciano, Italy.; Faquin WC; Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.; Pitman MB; Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.; Troncone G; Department of Public Health, University of Naples Federico II, Naples, Italy.
Source
Publisher: Wiley-Blackwell Country of Publication: United States NLM ID: 101499453 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1934-6638 (Electronic) Linking ISSN: 1934662X NLM ISO Abbreviation: Cancer Cytopathol Subsets: MEDLINE
Subject
Language
English
Abstract
Background: In a previous worldwide survey, the authors showed a drastic reduction in the number of cytological specimens processed during the coronavirus disease 2019 "lockdown" period along with an increase in malignancy rates. To assess the continued impact of the pandemic on cytological practices around the world, they undertook a second follow-up worldwide survey collecting data from the post-lockdown period (2020).
Methods: Participants were asked to provide data regarding their cytopathology activity during the first 12 weeks of their respective national post-lockdown period (2020), which ranged from April 4 to October 31. Differences between the post-lockdown period and the corresponding 2019 period were evaluated, and the authors specifically focused on rates of malignant diagnoses.
Results: A total of 29 respondents from 17 countries worldwide joined the survey. Overall, a lower number of cytological specimens (n = 236,352) were processed in comparison with the same period in 2019 (n = 321,466) for a relative reduction of 26.5%. The overall malignancy rate showed a statistically significant increase (12,442 [5.26%] vs 12,882 [4.01%]; P < .001) during the same time period. Similar results were obtained if both malignancy and suspicious for malignancy rates were considered together (15,759 [6.58%] vs 16,011 [4.98%]; P < .001).
Conclusions: The data showed a persistent reduction in the cytological specimen volume during the post-lockdown period (2020). However, the relative increase in the cytological workload in the late part of the post-lockdown is a promising finding of a slow return to normality.
(© 2022 American Cancer Society.)
Methods: Participants were asked to provide data regarding their cytopathology activity during the first 12 weeks of their respective national post-lockdown period (2020), which ranged from April 4 to October 31. Differences between the post-lockdown period and the corresponding 2019 period were evaluated, and the authors specifically focused on rates of malignant diagnoses.
Results: A total of 29 respondents from 17 countries worldwide joined the survey. Overall, a lower number of cytological specimens (n = 236,352) were processed in comparison with the same period in 2019 (n = 321,466) for a relative reduction of 26.5%. The overall malignancy rate showed a statistically significant increase (12,442 [5.26%] vs 12,882 [4.01%]; P < .001) during the same time period. Similar results were obtained if both malignancy and suspicious for malignancy rates were considered together (15,759 [6.58%] vs 16,011 [4.98%]; P < .001).
Conclusions: The data showed a persistent reduction in the cytological specimen volume during the post-lockdown period (2020). However, the relative increase in the cytological workload in the late part of the post-lockdown is a promising finding of a slow return to normality.
(© 2022 American Cancer Society.)