학술논문

Prevalence of pulmonary artery dilation in non-cystic fibrosis bronchiectasis: A CT analysis from a cohort of the US Bronchiectasis and Nontuberculous Mycobacteria Research Registry.
Document Type
Author
Karamooz E; Oregon Health & Science University Pulmonary & Critical Care.; Brixey AG; Cardiothoracic Imaging Section, Department of Diagnostic Radiology, Oregon Health & Science University.; Rydzak CE; Cardiothoracic Imaging Section, Department of Diagnostic Radiology, Oregon Health & Science University.; Primack SL; Cardiothoracic Imaging Section, Department of Diagnostic Radiology, Oregon Health & Science University.; Markwardt S; Oregon Health & Science University-Portland State University School of Public Health.; Barker AF; Oregon Health & Science University Pulmonary & Critical Care.
Source
Country of Publication: United States NLM ID: 101768035 Publication Model: Electronic Cited Medium: Internet NLM ISO Abbreviation: Res Sq Subsets: PubMed not MEDLINE
Subject
Language
English
Abstract
Although pulmonary artery (PA) dilation is independently associated with significant morbidity and mortality in patients with pulmonary diseases irrespective of diagnosed pulmonary hypertension, its relationship to nontuberculous mycobacteria (NTM) is unknown. To determine the prevalence of PA dilation in patients with NTM-predominant non-CF bronchiectasis, we evaluated the chest computed tomography (CT) scans from 321 patient in the United States based Bronchiectasis and NTM Research Registry. The majority of our cohort had NTM infection. We measured the severity of bronchiectasis using modified Reiff criteria and measured the diameters of the PA and aorta (Ao), with PA dilation defined as a PA:Ao ratio > 0.9. Forty-two patients (13%) were found to have PA dilation. PA dilation was positively associated with the use of supplemental oxygen ( p < 0.001), but there was no association between PA dilation and NTM infection.
Competing Interests: Competing Interests The authors have no relevant financial or non-financial interests to disclose.

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