학술논문
Risk Factor Analysis of Complications and Mortality Following Coil Procedures in Patients with Intracranial Unruptured Aneurysms Using a Nationwide Health Insurance Database.
Document Type
Academic Journal
Author
Park SY; Department of Medicine, College of Medicine, Yeungnam University, Daegu 42415, Republic of Korea.; Kim SA; Department of Medicine, College of Medicine, Yeungnam University, Daegu 42415, Republic of Korea.; An YH; Department of Medicine, College of Medicine, Yeungnam University, Daegu 42415, Republic of Korea.; Kim SW; Medical Research Center, College of Medicine, Yeungnam University, Daegu 42415, Republic of Korea.; Kim S; Department of Pediatrics, College of Medicine, Yeungnam University, Daegu 42415, Republic of Korea.; Lee JM; Department of Pediatrics, College of Medicine, Yeungnam University, Daegu 42415, Republic of Korea.; Jung Y; Department of Neurosurgery, Yeungnam University Medical Center, Daegu 42415, Republic of Korea.
Source
Publisher: MDPI AG Country of Publication: Switzerland NLM ID: 101606588 Publication Model: Electronic Cited Medium: Print ISSN: 2077-0383 (Print) Linking ISSN: 20770383 NLM ISO Abbreviation: J Clin Med Subsets: PubMed not MEDLINE
Subject
Language
English
ISSN
2077-0383
Abstract
(1) Background: Unruptured intracranial aneurysm (UIA) occurs in 1-2% of the population and is being increasingly detected. Patients with UIA are treated with close observation, endovascular coiling or surgical clipping. The proportion of endovascular coiling has been rising. However, complications such as cerebral infarction (CI), intracranial hemorrhage (ICRH), and death remain crucial issues after coil treatment. (2) Methods: We analyzed the incidence and risk factors of complications after the use of coil in patients with UIA based on the patients' characteristics. We utilized the Health Insurance Review and Assessment (HIRA) database. Patients treated with coils for UIA between 1 January 2015 and 1 December 2021 were retrospectively analyzed. (3) Results: Of the total 35,140 patients, 1062 developed ICRH, of whom 87 died, with a mortality rate of 8.2%. Meanwhile, 749 patients developed CI, of whom 29 died, with a mortality rate of 3.9%. The overall mortality rate was 1.8%. In a univariate analysis of the risk factors, older age, males, a higher Charlson Comorbidity Index (CCI) score, and diabetes increase the risk of CI. Meanwhile, males with higher CCI scores and hemiplegia or paraplegia show increased ICRH risk. Older age, males and metastatic solid tumors relate to increased mortality risk. (4) Conclusions: This study is significant in that the complications based on the patient's underlying medical condition were analyzed.