학술논문
Bioactive molecules from ciliates: Structure, activity, and applicative potential.
Document Type
Academic Journal
Author
Alimenti C; Laboratory of Eukaryotic Microbiology and Animal Biology, School of Biosciences and Veterinary Medicine, University of Camerino, Camerino, Italy.; Buonanno F; Laboratory of Protistology and Biology Education, Department of Education, Cultural Heritage, and Tourism (ECHT), Università degli Studi di Macerata, Macerata, Italy.; Di Giuseppe G; Unit of Protistology, Department of Biology, University of Pisa, Pisa, Italy.; MARinePHARMA Center, University of Pisa, Pisa, Italy.; Guella G; Bioorganic Chemistry Lab, Department of Physics, University of Trento, Trento, Italy.; Luporini P; Laboratory of Eukaryotic Microbiology and Animal Biology, School of Biosciences and Veterinary Medicine, University of Camerino, Camerino, Italy.; Ortenzi C; Laboratory of Protistology and Biology Education, Department of Education, Cultural Heritage, and Tourism (ECHT), Università degli Studi di Macerata, Macerata, Italy.; Vallesi A; Laboratory of Eukaryotic Microbiology and Animal Biology, School of Biosciences and Veterinary Medicine, University of Camerino, Camerino, Italy.
Source
Publisher: Wiley Country of Publication: United States NLM ID: 9306405 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1550-7408 (Electronic) Linking ISSN: 10665234 NLM ISO Abbreviation: J Eukaryot Microbiol Subsets: MEDLINE
Subject
Language
English
Abstract
Ciliates are a rich source of molecules synthesized to socialize, compete ecologically, and interact with prey and predators. Their isolation from laboratory cultures is often straightforward, permitting the study of their mechanisms of action and their assessment for applied research. This review focuses on three classes of these bioactive molecules: (i) water-borne, cysteine-rich proteins that are used as signaling pheromones in self/nonself recognition phenomena; (ii) cell membrane-associated lipophilic terpenoids that are used in interspecies competitions for habitat colonization; (iii) cortical granule-associated molecules of various chemical nature that primarily serve offence/defense functions.
(© 2022 The Authors. Journal of Eukaryotic Microbiology published by Wiley Periodicals LLC on behalf of International Society of Protistologists.)
(© 2022 The Authors. Journal of Eukaryotic Microbiology published by Wiley Periodicals LLC on behalf of International Society of Protistologists.)