학술논문

Prevalence and risk factors of functional seizures among adult Sudanese patients with epilepsy, a cross-sectional clinic-based study.
Document Type
Academic Journal
Author
Hussien Mohamed Ahmed KA; University of Khartoum, Faculty of Medicine, Khartoum, Sudan.; Elnaiem W; University of Khartoum, Faculty of Medicine, Khartoum, Sudan.; Abdalla YA; Omdurman Islamic University, Faculty of Medicine, Khartoum, Sudan.; Hamza SB; Omdurman Islamic University, Faculty of Medicine, Omdurman, Sudan.; Ibrahim M; University of Bahri, Faculty of Medicine, Teaching Assistant at Department of Internal Medicine, Khartoum North, Sudan.; Abdallah AM; University of Bahri, Faculty of Medicine, Police Hospital, Khartoum, Sudan.; Hajhamed M; Ahfad University for Women, Faculty of Medicine, Khartoum, Sudan.; Elfatih G; University of Khartoum, Faculty of Medicine, Omdurman, Sudan.; Fakhreldeen A; Ahfad University for Women, Faculty of Medicine, Omdurman, Sudan.; Hassan T; Ahfad University for Women, Faculty of Medicine, Khartoum North, Sudan.; Faisal R; Ahfad University for Women, Faculty of Medicine, Khartoum, Sudan.; Salih RA; Ahfad University for Women, Faculty of Medicine, Omdurman, Sudan.; Mahmoud MA; Ahfad University for Women, Faculty of Medicine, Khartoum, Sudan.; Ahmed M; Ahfad University for Women, Faculty of Medicine, Omdurman, Sudan.; Fadlallah Y; Omdurman Islamic University, Faculty of Medicine, Khartoum, Sudan.; Alhusseini RT; Alzaiem Alazhari University, Faculty of Medicine, Khartoum, Sudan.; Albasheer N; Ahfad University for Women, Faculty of Medicine, Khartoum, Sudan.; Shamsaldeen L; Ahfad University for Women, Faculty of Medicine, Omdurman, Sudan.; Mohammed L; Alzaiem Alazhari University, Faculty of Medicine, Khartoum, Sudan.; Siddig A; Al Neelain University, Faculty of Medicine, Khartoum, Sudan.; Alamin Alkhalifamohamed HM; University of Khartoum, Faculty of Medicine, Khartoum, Sudan.; Salih EH; University of Khartoum, Faculty of Medicine, Khartoum, Sudan.; Hussien A; University of Khartoum, Faculty of Medicine, Khartoum, Sudan.; Fadelallah Eljack MM; Community Department, University of Bakht Alruda, Ad Duwaym, Sudan.
Source
Publisher: Wolters Kluwer Country of Publication: England NLM ID: 101616869 Publication Model: eCollection Cited Medium: Print ISSN: 2049-0801 (Print) Linking ISSN: 20490801 NLM ISO Abbreviation: Ann Med Surg (Lond) Subsets: PubMed not MEDLINE
Subject
Language
English
ISSN
2049-0801
Abstract
Background: Epilepsy can be associated with functional seizures. Our main aim is to assess functional seizures' prevalence and risk factors among adult Sudanese patients with epilepsy.
Methods: This cross-sectional clinic-based study was conducted from January to February 2021 at Daoud Charity Clinic in Omdurman city, Sudan. Ninety-nine adult Sudanese patients with epilepsy were included. Data were collected using a validated interview-based semi-structured questionnaire. A senior consultant neurologist and a consultant psychiatrist diagnosed the functional seizures based on full clinical history and investigations. The diagnosis was performed according to International League against epilepsy (ILAE) classification.
Results: This study included 99 patients with epilepsy, 57% were females, 79% reside in Khartoum state, and 32% reached secondary school. The main types of epilepsy were generalized tonic-clonic (68%), followed by focal seizures with impaired awareness (11%). The majority of the patients have been diagnosed with epilepsy for over three years (65%). Comorbid epilepsy and functional seizures were found in 29% of the patients, with a significantly higher prevalence in patients with social problems and depression (p = 0.005 and p < 0.01, respectively). Patients with depression had a 14 times higher risk of functional seizures than those without depression, 95% CI [3.8, 52.3].
Conclusion: A remarkably high prevalence of functional seizures was found among adult patients with epilepsy. Patients suffering from social problems and/or depression and poor economic status had a higher tendency to develop functional seizures, especially after two to three years of treatment and above.
Competing Interests: All authors declare that there are no conflicts of interest.
(© 2022 The Authors.)