학술논문
Exposure Assessment and Inflammatory Response Among Workers Producing Calcium Carbonate Nanomaterials.
Document Type
Theses
Author
Source
Dissertation Abstracts International; Dissertation Abstract International; 74-11B(E).
Subject
Language
English
Abstract
Summary: Airway inflammatory responses presented a dose-response relationship using mass as exposure metric. The concentrations of IL1β (p =0.043) and IL8 (p=0.008) in sputum among high mass-exposure group were statistically greater than that in low-mass exposure group. It suggested the inflammatory responses were associated with mass concentration of inhaled nanoparticle particles, which are mainly made up by agglomerated form of nanoparticles. At current stage, with limited understanding of the toxicological perspective of nanoparticle, a complete exposure assessment in nanoparticle facility needs to be conducted in both bulk- and nano-form.