학술논문

Matched case-control data analyses with missing covariates.
Document Type
Article
Source
Journal of the Royal Statistical Society: Series C (Applied Statistics). Mar2000, Vol. 49 Issue 1, p145. 12p.
Subject
*Analysis of covariance
*Estimation theory
Multiple imputation (Statistics)
Language
ISSN
0035-9254
Abstract
We consider methods for analysing matched case-control data when some covariates (W) are completely observed but other covariates (X) are missing for some subjects. In matched case-control studies, the complete-record analysis discards completely observed subjects if none of their matching cases or controls are completely observed. We investigate an imputation estimate obtained by solving a joint estimating equation for log-odds ratios of disease and parameters in an imputation model. Imputation estimates for coefficients of W are shown to have smaller bias and mean-square error than do estimates from the complete-record analysis. [ABSTRACT FROM AUTHOR]