학술논문
Diagnosis and staging of superficial esophageal precursor based on pre-endoscopic resection system comparable to endoscopic resection.
Document Type
Article
Author
Source
Subject
*TREATMENT of esophageal cancer
*CANCER endoscopic surgery
*CANCER treatment
*SQUAMOUS cell carcinoma
*ABLATION techniques
*ACQUISITION of data
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Language
ISSN
1471-2407
Abstract
Background: Endoscopic treatments for early esophageal squamous cell carcinoma and the esophageal neoplasm are two types: endoscopic resection (ER) and ablation. Resection enables evaluation of the lesion in the ER specimens, while ablation cannot. We sought to establish a pre-ER evaluated system with a diagnostic and staging accuracy similar to ER for the development of ablation therapy. Methods: In our study, we collected data pertaining to early esophageal cancer and esophageal neoplasm treated with ER, analyzed the pre- and post-ER data of the lesions and evaluated the diagnostic accuracy of pre-ER system compared with the gold standard. Results: The diagnostic accuracy rate was 91% based on the pre-ER system compared with the gold standard, and 93% based on the ER diagnosis. The AUC of the pre-ER system was 0.964, while the ER examination was 0.971. Conclusion: These results suggest that the accuracy of pre-ER system was comparable to ER. The pre-ER system enables prediction of histological diagnosis and stage of the lesions, and the choice of treatment for superficial esophageal neoplasm. [ABSTRACT FROM AUTHOR]