학술논문
Supramolecular Assembly of Coronene Derivatives for Drug Delivery.
Document Type
Article
Author
Source
Subject
*SUPRAMOLECULES
*MOLECULAR self-assembly
*DRUG delivery systems
*CHEMICAL derivatives
*CHEMICAL synthesis
*MICROFABRICATION
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Language
ISSN
1523-7060
Abstract
Possessing a small size and C3-symmetrical rigid backbone, a coronene derivative was synthesized from β-cyclodextrins and hexa-cata-hexabenzocoronene, and then a water-soluble and biocompatible nanographene/polysaccharide supramolecular assembly was successfully fabricated through noncovalent interactions between adamantly grafted hyaluronic acids and β-cyclodextrin-modified hexa-cata-hexabenzocoronene. Moreover, the ternary supramolecular assembly showed not only a fluorescence imaging ability toward cancer cells but also good anticancer activity and low toxicity. [ABSTRACT FROM AUTHOR]