부산대학교 도서관

Background Idiopathic hypereosinophilic syndrome (IHES) is a syndrome with unexplained persistent elevation of eosinophils for more than 6 months, mainly involving the skin, cardiovascular, gastrointestinal, and nervous systems. Neurologic comorbidities of IHES include reports of cerebral infarction, encephalopathy, and peripheral nerve disorders, and about 35-65% of patients have some sort of neurological comorbidity [[6]]. The diagnosis of IHES requires to exclude significant peripheral eosinophilia from secondary (or reactive) causes of eosinophilia such as infection, hematologic malignancy, and vasculitis [[5]]. The patient showed the clinical presentation features such as prominent peripheral eosinophilia and central nervous system involvement, and vasculitis features and asthma are not obvious, so IHES is the more likely diagnosis. [Extracted from the article]