학술논문
Association of fracture incidence in children with the development of food allergy: A Korean nationwide birth cohort study.
Document Type
Article
Author
Kwon, Rosie; Shin, Youn Ho; Shin, Jae Il; Kang, So Min; Hwang, Jimin; Shin, Jung U.; Noh, Hyungrye; Heo, Chan Yeong; Koyanagi, Ai; Jacob, Louis; Smith, Lee; Ludvigsson, Jonas F.; Turner, Stephen; Shin, Ju‐Young; Jeong, Han Eol; Kim, Jung‐Hyun; Rhee, Sang Youl; Min, Chanyang; Suh, Dong In; Koo, Min Ji
Source
Subject
*MILK allergy
*BONE fractures
*CHILD nutrition
*FOOD allergy
*CHILD development
*COHORT analysis
*KOREAN cooking
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Language
ISSN
0105-4538
Abstract
To the Editor, Globally, the prevalence of food allergy (FA) in children is increasing, and FA can induce fatal anaphylaxis, which affects morbidity and mortality.[[1]] Children with FAs are more likely to have food neophobia, which may lead to severe vitamin D deficiency and osteoporosis. The earlier the development of FA, the higher the risk of fractures (aHR for the first FA diagnosis at <2 years, 1.19 [95% CI: 1.08-1.31]; aHR for the first FA diagnosis at 2-4 years, 1.09 [95% CI: 1.01-1.19]; and aHR for the first FA diagnosis at >=5 years, 1.14 [95% CI: 1.04-1.26]). The risk of fracture increased with increasing FA severity (fracture incidence rate [1000 person-years]: 36.60 for control vs. 40.63 for mild FA vs. 48.61 for moderate-to-severe FA). [Extracted from the article]