학술논문
DNA mismatch repair gene mutations in human cancer.
Document Type
Article
Author
Source
Subject
*MOLECULAR carcinogenesis
*DNA repair
*CANCER genetics
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Language
ISSN
1078-0475
Abstract
Identifies a pathogenic mechanism leading to cancer involving human homologues of DNA mismatch repair (MMR) genes. Discovery of human mismatch repair genes; Functions of the MMR system; Microsatellite instability and its occurrence in cancer; Model of carcinogenesis with MMR deficiency; Prospects.