학술논문
mcr-2 in the IncX4 plasmid pKP37-BE is flanked by directly oriented copies of ISEc69.
Document Type
Letter
Author
Source
Subject
*COLISTIN
*PLASMIDS
*GENETIC code
*AMINO acids in the body
*PAENIBACILLUS
*ANIMALS
*BACTERIAL proteins
*DRUG resistance in microorganisms
*ESCHERICHIA coli
*GENES
*GENETIC techniques
*MEMBRANE proteins
*PROTEINS
*TRANSFERASES
*GRAM-negative aerobic bacteria
*SEQUENCE analysis
*PHARMACODYNAMICS
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Language
ISSN
0305-7453
Abstract
The article discusses a study related to flanking of mcr-2 in the IncX4 plasmid pKP37-BE by directly oriented copies of ISEc69. Topics discussed include ISEc69 containing a gene encoding a protein with the highest amino acid identified for transposasing of the IS1016 group from the IS1595 family, shorter PAP2-like protein from pKP87-BE than the PAP-2 protein associated with mcr-1 and Paenibacillus, a species that produces polymyxins, as closest matches to MCR-1.