학술논문
Mediators of Inflammation in Bone Physiology and Diseases.
Document Type
Article
Author
Source
Subject
*BONE diseases
*OSTEITIS
*INFLAMMATORY mediators
*MAST cell disease
*BLOOD diseases
*BONE marrow cells
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Language
ISSN
0962-9351
Abstract
It is suggested that hypertryptasemia (high serum levels of mastocyte cell-specific serine protease tryptase) can be a useful marker of mastocyte-cell related diseases, such as bone fragility and secondary osteoporosis. Complex crosstalk between immune cells and cells involved in skeletal renewal is essential for bone health. Inflammatory insults in peri-implant areas, caused by the wear particles, provoke osteoclast activation at the bone-implant interface and initiate bone resorption. [Extracted from the article]