학술논문
Thymus in Experimental Carcinogenesis of the Prostate Gland.
Document Type
Article
Source
Subject
*PROSTATE cancer
*DIAGNOSIS
*CANCER complications
*CARCINOGENESIS
*THYMUS development
*ASCITES tumors
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Language
ISSN
0007-4888
Abstract
We studied structural changes in the prostate gland, thymus, and lymph nodes in CBA mice after transplantation of Ehrlich ascites tumor cells into the prostate gland. On experimental day 5, the number of blood and lymph vessels decreased in the gland; the percentage of connective tissue elements and glandular tissue and the number of immunoblasts in the thymus increased. On day 18, the number of blood vessels in the tumor decreased; the width of the cortex and glandular tissue increased in the thymus, while the number of immunoblasts was reduced. On day 28, tumor infiltration and increased number of lymphatic vessels in its stroma were observed; parenchyma was reduced, and the area of the connective tissue increased in the thymus. These structural changes indicated the development of accidental involution of the thymus during carcinogenesis of the prostate. [ABSTRACT FROM AUTHOR]