학술논문

Therapy of Type 2 Diabetes.
Document Type
Article
Source
Experimental & Clinical Endocrinology & Diabetes. 2022 Supplement 1, Vol. 130, pS80-S112. 33p.
Subject
*DIABETIC nephropathies
*HEART failure
*TYPE 2 diabetes
*HEALTH services administration
*SODIUM-glucose cotransporter 2 inhibitors
*MEDICAL societies
*WEIGHT loss
Language
ISSN
0947-7349
Abstract
In the differential diagnosis of the heterogeneous disease type 2 diabetes, subtypes of diabetes are increasingly defined and clinically considered in practice [12][13][14] Therapy Basic therapy Adapting to a healthy lifestyle is crucial not only to prevent type 2 diabetes, but also to reduce the complex pharmacotherapy and the development and progression of diabetic complications of type 2 diabetes. Flexibility of therapy decisions due to the heterogeneity of type 2 diabetes and individual therapy goals is necessary at every stage of treatment. Weight loss for excess weight For BMI from 27-35 kg/m 2: 5% weight reduction; for BMI 35 kg/m 2: 10% weight reduction Blood pressureSystolic blood pressure: 120-140 mmHg (>=65 years 130-140 mmHg; <=65 years 120-129 mmHg); diastolic blood pressure: 80 mmHg (not 70 mmHg); if the therapy has no relevant side effects 7 ht Lifestyle Blood pressure Glucose metabolism Lipid status Body weight B Prioritisation of the therapy goal on the basis of the personal risk profile b The guiding factors for the selection of the appropriate therapy strategy are the jointly prioritised therapy goals and the probability of benefiting from a certain therapy due to individual disease factors. EGFR = Estimated Glomerular Filtration Rate; DPP4-inhibitor = Dipeptidyl peptidase-4 inhibitor; GLP-1 RA = Glucagon-like peptide-1 receptor agonist; SGLT2 = Sodium-glucose cotransporter-2 The basic therapy at every therapy level comprises lifestyle-modifying, non-drug therapy measures, but these are often not sufficient on their own. [Extracted from the article]