학술논문
Diagnosis and management of an endometrial cancer patient with Cowden syndrome.
Document Type
Article
Author
Source
Subject
*ENDOMETRIAL cancer
*CANCER patients
*SYNDROMES
*DIAGNOSIS
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*
*
Language
ISSN
0090-8258
Abstract
Somatic PTEN alterations are common in endometrial carcinoma (EC), but in rare cases PTEN mutations are associated with inherited syndromes. Here, we present a case of Cowden syndrome-associated EC. We discuss clinical, pathologic and molecular features of her tumor and PTEN -mutated EC, inherited syndromes predisposing to EC and PTEN- targeted therapies. [ABSTRACT FROM AUTHOR]