학술논문
Acinetobacter baumannii Infection and IL-17 Mediated Immunity.
Document Type
Article
Author
Source
Subject
*ACINETOBACTER infections
*ACINETOBACTER baumannii
*INTERLEUKIN-17
*NOSOCOMIAL infections
*NEUTROPHIL immunology
*HOST-parasite relationships
*IMMUNE response
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Language
ISSN
0962-9351
Abstract
Acinetobacter baumannii is a significant cause of severe hospital-acquired infections with a recent rise in multidrug-resistant infections involving traumatic wounds of military personnel. The interleukin-17 (IL-17) pathway is essential for neutrophil recruitment in response to a variety of pathogens, while the control of A. baumannii infection is known to be dependent on neutrophils. This suggests that IL-17 may play an important role in A. baumannii infection; however, this has yet to be studied. Here, we summarize the recent advances in understanding the host-pathogen interaction of A. baumannii and propose a potential role of the IL-17 pathway in generating a protective immune response. [ABSTRACT FROM AUTHOR]