학술논문
Increased insulin‐like growth factor‐1 levels in a patient with pemphigus vulgaris.
Document Type
Article
Source
Subject
*PEMPHIGUS
*SOMATOMEDIN
*VASCULAR endothelial growth factors
*TRANSFORMING growth factors
*ACROMEGALY
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Language
ISSN
1396-0296
Abstract
Many pathogenetic antigens were identified for pemphigus vulgaris (PV), but there are no data about the association with insulin-like growth factors (IGFs). Both growth hormone (GH) and IGF-1 were found in normal reference ranges (GH: 0.4 [0-3.5 ng/mL] and IGF-1: 132) at the beginning of the diagnosis. Animal studies showed that steroid therapy reduces IGF-1 level.3 In our case, we observed a decline in the course of the levels of IGF-1 and IGFBP-3 after steroid therapy. [Extracted from the article]