학술논문

Encoding asymmetry within neural circuits.
Document Type
Article
Source
Nature Reviews Neuroscience. Dec2012, Vol. 13 Issue 12, p832-843. 12p. 4 Graphs.
Subject
*NERVOUS system
*NEURAL circuitry
*ENVIRONMENTAL impact analysis
*GENETICS
*COGNITION
*VERTEBRATES
Language
ISSN
1471-003X
Abstract
Genetic and environmental factors control morphological and functional differences between the two sides of the nervous system. Neural asymmetries are proposed to have important roles in circuit physiology, cognition and species-specific behaviours. We propose two fundamentally different mechanisms for encoding left-right asymmetry in neural circuits. In the first, asymmetric circuits share common components; in the second, there are unique unilateral structures. Research in both vertebrates and invertebrates is helping to reveal the mechanisms underlying the development of neural lateralization, but less is known about the function of circuit asymmetries. Technical advances in the coming years are likely to revolutionize our understanding of left-right asymmetry in the nervous system. [ABSTRACT FROM AUTHOR]