부산대학교 도서관

Thirty percent of Guillain-Barré syndrome ( GBS) patients require mechanical ventilation (MV) in intensive care unit ( ICU). Post-traumatic stress disorder ( PTSD) is found in ICU survivors, and the traumatic aspects of intubation and MV have been previously reported as risk factors for PTSD after ICU. Our objective was to determine long-term PTSD or post-traumatic stress symptoms (PTSS) in GBS patients after prolonged MV in ICU. We assessed GBS patients who had MV for more than 2 months. PTSD was assessed using Horowitz Impact of Event Scale ( IES), IES-Revisited ( IES-R), and the Post-traumatic CheckList Scale; functional outcome using Rankin and Barthel scales; quality of life ( QoL) using Nottingham Health Profile ( NHP) and 36-Item Short Form Health Survey ( SF-36) and depression using Hospital Anxiety and Depression Scale ( HAD) and Beck questionnaire. Thirteen patients could be identified and analyzed. They had only mild disability. They were neither anxious nor depressed with an anxiety HAD at 5 (4-11.5), a depression HAD at 1 (0-3.5) and a Beck at 1 (0-5). QoL was mildly decreased in our population with a NHP at 78.5 (12.8-178.8) and mild decreased SF-36. Compared with the French population, the SF-36 sub-categories were, however, not statistically different. Twenty-two percentage of our 13 patients had PTSD and PTSS with a Horowitz IES at 12 (2-29), and an IES-R at 16 (2-34.5). Although severe GBS patients requiring prolonged MV had good functional recovery and no difference in QoL, they had a high incidence of PTSS. [ABSTRACT FROM AUTHOR]