학술논문

Catastrophic Antiphospholipid Syndrome in Immune Thrombocytopenic Purpura -- Beyond Tenuous Concomitance!
Document Type
Article
Source
Indian Journal of Nephrology. Nov/Dec2020, Vol. 30 Issue 6, p424-426. 3p.
Subject
*KIDNEY disease diagnosis
*ACUTE kidney failure
*ANTIPHOSPHOLIPID syndrome
*AUTOANTIBODIES
*CATASTROPHIC illness
*THROMBOPENIC purpura
*DISEASE complications
Language
ISSN
0971-4065
Abstract
Significance of antiphospholipid antibodies in immune thrombocytopenic purpura is debatable and pose a diagnostic and therapeutic dilemma. Catastrophic antiphospholipid syndrome is a rare life-threatening entity, occurring in patients with antiphospholipid syndrome, usually after a triggering event. We describe an adult lady of chronic immune thrombocytopenic purpura (in remission) with antiphospholipid antibodies, who presented with rapidly progressive renal failure and had primary antiphospholipid syndrome nephropathy. The index manuscript titled exemplifies the fact that although the presence of APLA in ITP is known, however, management in the absence of clinical event remains debatable and may carry a future risk of thrombotic event/s mandating close monitoring with a high index of suspicion. [ABSTRACT FROM AUTHOR]