부산대학교 도서관

Both the American and European guidelines recommend in-hospital initiation of guideline-directed medical therapy and multiple experts have proposed algorithms for rapid initiation and titration of these drugs. It will be a travesty if the STRONG-HF trial results are ignored or are implemented recklessly, leading to predictable side effects and intolerances that will set a negative dynamic against rapid guideline-directed medical therapy implementation, which is avoidable. Keywords: heart failure; mineralocorticoid receptor antagonists; therapeutics EN heart failure mineralocorticoid receptor antagonists therapeutics 1189 1191 3 04/14/23 20230418 NES 230418 Rapid optimization of quadruple foundational therapy for heart failure (HF) with reduced ejection fraction comprising -blockers, angiotensin receptor neprilysin inhibitors, mineralocorticoid receptor antagonists (MRAs), and sodium-glucose cotransporter-2 inhibitors has been advocated recently. [Extracted from the article]