학술논문

A Practical ECG Criterion to Unmask Left Accessory AV Connections in Patients With Subtle Preexcitation.
Document Type
Article
Source
Journal of Cardiovascular Electrophysiology. Sep2015, Vol. 26 Issue 9, p978-984. 7p. 1 Diagram, 2 Charts, 3 Graphs.
Subject
*WOLFF-Parkinson-White syndrome treatment
*VENTRICULAR arrhythmia
*ACADEMIC medical centers
*CATHETER ablation
*ELECTROCARDIOGRAPHY
*ELECTRODIAGNOSIS
*FISHER exact test
*CARDIAC patients
*LONGITUDINAL method
*PROBABILITY theory
*RESEARCH funding
*T-test (Statistics)
*WOLFF-Parkinson-White syndrome
*DATA analysis software
*DESCRIPTIVE statistics
*DIAGNOSIS
Language
ISSN
1045-3873
Abstract
New ECG Criteria for Left-Sided AV Connections Background Accessory AV-connections capable of antegrade conduction need to be recognized because of the potential for life-threatening arrhythmias. However, the preexcited ECG pattern may be subtle, especially among left-sided AV-connections. We explored whether additional ECG criteria might help identify left-sided AV-connections. Methods We analyzed 156 patients who underwent an electrophysiology study (EPS) and ablation for paroxysmal supraventricular tachycardias (PSVT). Patients were divided into 2 groups: those with left-sided AV-connections (Group 1) and all other PSVT (Group 2). Various ECG parameters were compared before and after ablation in both groups. Results The EPS identified left-sided AV-connections among 43 patients (Group 1) and excluded it among 113 (Group 2). Baseline ECG in Group 1 demonstrated obvious preexcitation among 24/43 patients (55.8%), the remaining 19/43 missing obvious preexcitation. R/S ratio > 0.5 in V1 was noted in 38/43 (88.4%) patients in Group 1 before ablation (median 1.00; IQR 0.58-2.20), including 16/19 (84.2%) patients lacking obvious left-sided AVconnections. Conversely, only 10/113 (8.8%) patients in Group 2 had R/S ratios in V1 ≥ 0.5 (0.20; 0.10-0.31), P < 0.0001. After ablation, the R/S ratio decreased significantly in Group 1 (0.29; 0.17-0.45), P < 0.0001. Thus, a combined criterion of classic preexcitation or R/S ratio ≥ 0.5 on ECG identified 40/43 left-sided AV-connections (sensitivity 93.0%). The negative predictive value of this combined criterion was 103/106 (97.2%). Conclusions In symptomatic patients, combining the R/S ratio (≥ 0.5) in lead V1 with the classic preexcitation pattern on ECG markedly improved the sensitivity to diagnose left-sided AV-connections. This ratio may be particularly useful among patients lacking obvious preexcitation. [ABSTRACT FROM AUTHOR]