학술논문

Sunitinib in Patients With Metastatic Renal Cell Carcinoma.
Document Type
Article
Source
JAMA: Journal of the American Medical Association. 6/7/2006, Vol. 295 Issue 21, p2516-2524. 9p. 3 Black and White Photographs, 7 Diagrams, 6 Charts, 2 Graphs.
Subject
*CANCER treatment
*RENAL cell carcinoma
*PROTEIN-tyrosine kinase inhibitors
*CLINICAL trials
*CANCER research
*MEDICAL research
*CANCER patient rehabilitation
*RENAL cancer
*CLINICAL pharmacology
*CLINICAL medicine
*THERAPEUTICS
Language
ISSN
0098-7484
Abstract
This article presents a study focusing on the usefulness of sunitinib malate, an oral multitargeted tyrosine kinase inhibitor, as an additional aid in the standard treatment of patients with metastatic clear-cell renal cell carcinoma (RCC). The study incorporated a clinical trial which examined patients treated with sunitinib malate during the progression of their disease. Researchers examined the development of tumors and monitored the survival rate of the controlled group. The study found that sunitinib malate was almost uniformly successful in RCC and resulted in only minor side-effects for a small percentage of these patients.