학술논문
Graft-versus-host driven graft-versus-leukemia effect of minor histocompatibility antigen HA-1 in chronic myeloid leukemia patients.
Document Type
Article
Source
Subject
*CHRONIC myeloid leukemia
*LEUKEMIA
*LEUCOCYTES
*STEM cell transplantation
*GRAFT versus host disease
*BONE marrow transplant complications
*PATIENTS
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Language
ISSN
0887-6924
Abstract
The article focuses on the effect of minor histocompatibility antigen HA-1 on patients with chronic myeloid leukemia. It observes that the human leukocyte antigen and stem cell transplantation (SCT) proves that the graft versus leukemia (GvL) effect and graft versus host disease (GvHD) develops by the result of cellular allo-immune. It concludes that the contribution of a single hematopoietic-mHag to the reduction of leukemia relapse rates depends upon the response of alloreactive T-cell.