학술논문
Synthesis of Kojic Acid Derivatives Containing Phenolic Hydroxy Groups.
Document Type
Article
Author
Source
Subject
*BIOSYNTHESIS
*PHENOLS
*HYDROXY acids
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Language
ISSN
0039-7911
Abstract
Two kojic acid derivatives (2a and 2b) containing phenolic hydroxy groups were synthesized. The preparation was carried out by the reaction of a kojic acid derivative (3) having a chloromethyl group with phenol derivatives (4 and 7), followed by the subsequent deprotection steps. The first reaction proceeded smoothly in the presence of potassium carbonate in DMF at room temperature. Then, the appropriate deprotection reactions gave the desired compounds 2a and 2b. The structures of 2a and 2b were confirmed by the 1H NMR spectra. [ABSTRACT FROM AUTHOR]