학술논문

Regulation of eosinophil membrane depolarization during NADPH oxidase activation.
Document Type
Article
Source
Journal of Cell Science. 8/01/2003, Vol. 116 Issue 15, p3221-3226. 6p. 1 Color Photograph, 6 Graphs.
Subject
*PHORBOL esters
*EOSINOPHILS
Language
ISSN
0021-9533
Abstract
Describes the effects of phorbol ester (PMA) on the membrane potential of eosinophils using a cell-permeable oxonol membrane potential indicator, bis-barbituric acid oxonol to determine the extent of depolarization. Activation of NADPH oxidase-associated proton channel under conditions where superoxide is produced; Importance of protein kinase C for PMA-induced depolarization.