학술논문

Histiocytic erythema multiforme.
Document Type
Article
Source
Journal of Cutaneous Pathology. Dec2009, Vol. 36 Issue 12, p1323-1325. 3p. 3 Color Photographs.
Subject
*ERYTHEMA multiforme
*DEGENERATION (Pathology)
*KERATINOCYTES
*LYMPHOCYTES
*ETIOLOGY of diseases
*DISEASES
Language
ISSN
0303-6987
Abstract
Erythema multiforme is histologically characterized by liquefactive degeneration along the dermal-epidermal junction, necrotic keratinocytes and a lymphocytic infiltrate. We report a 10-year-old boy with recurrent erythema multiforme major of undetermined etiology with unusual histologic findings. A skin biopsy taken at day 2 of his eruption revealed histologic features otherwise characteristic of erythema multiforme, but mediated instead by a CD68-positive infiltrate, resembling cutaneous Kikuchi's disease. To the best of our knowledge this is the first reported case of ‘histiocytic’ erythema multiforme. [ABSTRACT FROM AUTHOR]