학술논문

Structure of human translin at 2.2 Å resolution.
Document Type
Article
Source
Acta Crystallographica: Section D (Wiley-Blackwell). Apr2004, Vol. 60 Issue 4, p674-679. 6p.
Subject
*TETRAMERS (Oligomers)
*MONOMERS
*SPACE groups
*CRYSTALS
*DNA
*RNA
*HUMAN beings
Language
ISSN
0907-4449
Abstract
The structure of human translin at 2.2 Å resolution is reported in space group C2221. Translin forms a tetramer in the asymmetric unit. Although the monomer structure is almost the same as the crystal structure of murine translin in space group P21212, the relative positions of the tetramers differ between the human and murine translins. This suggests that the multimerization of translin is flexible; the flexibility may be related to the binding to DNA/RNA. [ABSTRACT FROM AUTHOR]