학술논문

Mapping regional grey and white matter atrophy in relapsing–remitting multiple sclerosis.
Document Type
Article
Source
Multiple Sclerosis Journal. Jul2012, Vol. 18 Issue 7, p1027-1037. 11p. 4 Color Photographs, 3 Charts.
Subject
*MULTIPLE sclerosis
*ATROPHY
*MAGNETIC resonance imaging
*MORPHOMETRICS
*DISEASE duration
*GENDER
*PATIENTS
Language
ISSN
1352-4585
Abstract
The article discusses a study which investigates the regional distribution of white matter (WM) and grey matter (GM) atrophy in relapsing-remitting multiple sclerosis (RRMS) patients. Magnetic resonance imaging and voxel-based morphometry (SPM8) were used to obtain the data from 78 RRMS patients and 88 controls. It reveals the distinct regional distribution of GM and VM in RRMS patients, in which disease duration, gender, and disability affect the topography of WM/GM atrophy.