학술논문
Predicted vCJD mortality in Great Britain.
Document Type
Article
Source
Subject
*CREUTZFELDT-Jakob disease
*BOVINE spongiform encephalopathy
*MORTALITY
*GENOTYPE-environment interaction
*FORECASTING
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Language
ISSN
0028-0836
Abstract
Predicts variant Creutzfeldt-Jakob disease (vCJD) mortality in Great Britain in the wake of a bovine spongiform encephalopathy (BSE) epidemic in cattle. Use of scenario analysis; Finding that data are consistent with between 63 and 136,000 cases among the population known to have a susceptible genotype (having two copies of the methionine codon at codon 129 of the PrP gene) with on average less than two cases of vCJD arising from the consumption of one infected bovine.