부산대학교 도서관

Aim Pain symptoms are part of daily life in adults with CF, with an important impact on QOL. The aim of this study is to compare the prevalence of pain in adults with CF, with and without lung transplantation (TX). Method A cross-sectional, descriptive study was performed. Patients at the outpatient clinic were asked to fill in the Cystic Fibrosis Questionnaire; Brief Pain Inventory – short form and McGill questionnaire. Clinical data were collected from the patients files. Results From 90 participants, 50 were non-transplant CF patients. 59 participants were homozygous for DF 508, 28 heterozygous and 3 carried other mutations. Characteristic Value Transplantation No transplantation Males (n = 12) Females (n = 28) Males (n = 29) Females (n = 21) Mean age, y 34.58 (10.457) 34.96 (9.845) 28.28 (8.035) 29.81 (6.030) Mean FVC, % 77.67 (14.606) 86.07 (16.673) 91.07 (20.190) 85.24 (17.085) Mean FEV1, % 73.50 (26.916) 72.46 (22.128) 68.83 (22.901) 64.14 (21.618) Acute pain, n (%) 2 (17%) 8 (29%) 11 (38%) 6 (29%) Daily pain, n (%) 7 (58%) 16 (57%) 13 (45%) 9 (43%) Values are mean (SD) unless otherwise noted. Values are mean (SD) unless otherwise noted. Conclusion From all male participants 32% reported acute pain (17% TX), 56% reported daily pain (7% TX). 29% of female participants reported acute pain (29% TX), 51% daily pain (57% TX) with important impact on daily life. In TX men there was a reduced frequency of acute pain as compared to non-TX men with CF, but this difference was not significant (p = 0.27). In women, there was no difference in frequency of pain reporting between TX and non-TX patients. Pain is frequent in all CF adults and should be assessed frequently. LungTX does not result in an improvement of pain reporting. Further research is needed to implement a patient-centered pain-management system. [ABSTRACT FROM AUTHOR]