학술논문

Shirazi thyme (Zataria multiflora) extract can alleviate allergic rhinitis: a randomized clinical trial.
Document Type
Article
Source
Advances in Dermatology & Allergology / Postępy Dermatologii i Alergologii. 2021, Vol. 38 Issue 3, p520-525. 6p.
Subject
*ALLERGIC rhinitis
*ALLERGIES
*THYMES
*PLANT extracts
*ANTI-inflammatory agents
*HERBAL medicine
*CLINICAL trials
Language
ISSN
1642-395X
Abstract
Introduction: Atopic diseases are global concerns in the today's industrialized world. Allergic rhinitis is the most common allergic condition affection 20% of individuals. This disorder is associated with markable morbidity and rising healthcare expenditure. Aim: Considering the anti-inflammatory properties of a plant Zataria multiflora (ZM) with the common name of Shirazi thyme, a randomized clinical trial was designed to evaluate the alleviation of the symptoms of allergic rhinitis. Material and methods: A total of 30 allergic rhinitis patients were randomly and equally assigned to experimental and control groups. Afterwards, the case group was treated with an extract of ZM and the control group with placebo for 2 months. Finally, the clinical signs and symptoms before and after the treatment according to the SNOT22 questionnaire were analysed. Results: Comparing the symptoms of allergic rhinitis and an average score of SNOT22 questionnaire between the two groups before the intervention provided some difference, which was significantly greater after the treatment. Based on this questionnaire, our patients in the ZM syrup group had lower grades than before the treatment and experienced ameiloration.Conclusions: Regarding the significant effect of the ZM syrup in reducing symptoms of allergic rhinitis, its use is highly recommended. Since allergic rhinitis is a multifactorial condition, the use of herbal antioxidants along with conventional treatment would result in a more effective improvement of the disease. [ABSTRACT FROM AUTHOR]