학술논문
A pH-responsive asymmetric lipid vesicle as drug carrier.
Document Type
Article
Author
Source
Subject
*DRUG carriers
*LIPID analysis
*PH effect
*MICROFLUIDICS
*SILANE
*FOURIER transform infrared spectroscopy
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Language
ISSN
0265-2048
Abstract
In order to increase the loading efficiency of drug carriers, here we demonstrated a microfluidic method to fabricate an asymmetric vesicle, which contains trichloro(1H,1H,2H,2H-perfluoroocty-l)silane (TPS) inner leaflet and lipid outer leaflet. The asymmetric vesicle was characterised by fluorescence microscopy and Fourier transform infra-red spectrum.In vitrocytotoxicity of the vesicles carrying 5-fluorouacil (5-FU) has also been studied. [ABSTRACT FROM PUBLISHER]