학술논문
Enhanced Oxidative Stress and Physiological Damage in Daphnia magna by Copper in the Presence of Nano-TiO2 .
Document Type
Article
Author
Source
Subject
*NANOSTRUCTURED materials
*AQUATIC organisms
*OXIDATIVE stress
*DAPHNIA magna
*TITANIUM oxides
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Language
ISSN
1687-4110
Abstract
This study examines the potential hazard of an individual nanomaterial on the Cu biotoxicity to aquatic organisms. Daphnia magna in the absence or presence of nano-TiO2 was exposed to Cu. Maintaining nano-TiO2 at a safe concentration cannot eliminate its potential hazard. The biomarkers superoxide dismutase, catalase, and Na+/k+-ATPase in D. magna were measured. Cu in the presence of nano-TiO2 induced higher levels of oxidative stress and physiological damage because of the sorption of Cu. Nano-TiO2 also caused Na+/k+-ATPase inhibition possibly by impeding the Na+/k+ transfer channel. The correlations among the biomarkers, mortality, and accumulation further showed that the overloading reactive oxygen species generation caused by nano-TiO2 contributed to deeper oxidative stress and physiological regulation, thereby causing greater toxic injury. [ABSTRACT FROM AUTHOR]